State-of-the-art of Percutaneous Laser Ablation for Thyroid Micropapillary Carcinoma.


Comment by Dr Roberto Novizio.

This lecture focuses on the use of laser for the treatment of thyroid micropapillary  tumors.

More in general, ultrasound-guided thermal ablation is a non-surgical ( technique that has been primary used for reduction of benign thyroid nodules, but has also been proposed for treating well-differentiated thyroid carcinoma. 

Thyroid cancer is the most common endocrine malignancy. The incidence of thyroid cancer was relatively stable until the early 90s, after which it substantially increased. All the increased diagnoses is virtually attributable to an increase in papillary thyroid cancer. However, thyroid cancer mortality has remained stable over the 25-year period: so, it does not seem to be an epidemic of the disease, but an epidemic of diagnosis, that can generate an over-treatment in people who may never develop symptoms.

Some scientists started focusing on thermal ablative therapies to treat Papillary MicroCarcinoma since 2011.

Percutaneous laser ablation was one of the first techniques used to perform thyroid thermal ablation.

High-quality evidences proving the efficacy and safety of those technique for PTMC are lacking so it is not surprising that thermal ablative techniques were not mentioned in the 2015 guidelines.

In this presentation analyze the state-of-the-art about the use of laser ablation therapy in PTMC.